Exposure to amlodipine in the first trimester of pregnancy and during breastfeeding

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    Studies on animals show that administering this medication prior to mating, throughout mating, and during gestation significantly reduced litter size, increased intrauterine deaths, prolonged gestation, and increased labor duration. There are no controlled data in human pregnancy. Some patients receiving calcium channel blockers experienced reversible biochemical changes in the head of the spermatozoa. Although this medication lacks controlled data, animal models have demonstrated negative effects on male fertility. Drugs that, due to their pharmacological effects, have caused or may be suspected of causing negative effects on the human fetus or neonate without leading to malformations fall under the AU TGA pregnancy category C. These effects may be reversible. Accompanying texts should be consulted for further details. US FDA pregnancy category C: There are no adequate and well-controlled human studies and animal reproduction studies have shown an adverse effect on the fetus, but potential benefits may justify use of the drug in pregnant women despite potential risks.

    Use is contraindicated in the UK, Australia, and the United States. Excreted into human milk: Yes Comments: -The effects on the nursing infant are unknown. A decision should be made regarding whether to stop breastfeeding or stop taking the medication. -Infants exposed to this drug should be closely monitored.

    AU TGA pregnancy category: C US FDA pregnancy category: CComments: -Use of adequate methods of contraception should be encouraged. Use of this medication during pregnancy should only be done if the benefit outweighs the risk to the fetus. -The patient should be informed of the potential risks to the fetus if this medication is used during pregnancy or if the patient becomes pregnant while taking this medication.

    What if I prefer not to take medicines in pregnancy?

    Given that these conditions can have serious consequences for both mother and child, it is crucial to take any medications prescribed for high blood pressure or heart issues. Untreated high blood pressure can result in serious illnesses for both the mother and the baby, preterm birth, and low infant birth weight. Furthermore, it is crucial for the woman’s health that any condition that significantly lowers quality of life is kept under control. Only when necessary will a doctor recommend medications, and he or she is willing to address any worries.

    Blood Pressure Meds During Pregnancy | Safe BP Medications During Pregnancy and Breast Feeding

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